Unconjugated Rabbit anti-Human, Mouse, Rat, Dog IGF 1 Polyclonal Antibody [IgG]

IGFI; IGF-I; IGF1A; Insulin-like growth factor I; Mechano growth factor; MGF; Somatomedin-C; IGF1; IBP1

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.