Unconjugated Rabbit anti-Human, Rat ChRM2 Polyclonal Antibody [IgG]

HM2; Muscarinic acetylcholine receptor M2; CHRM2

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.