TLR2 Polyclonal Antibody
Výrobce: Bioss Katalogové č.: bs-1019R Aplikace: Western Blot, Imunofluorescence, Imunohistochemie, Průtoková cytometrie Reaktivita: Human, Mouse, Rat, Sheep, Bovine Původ: Rabbit Klonalita: Polyclonal Podtřída: IgG Status: RUO Dodatečné informace: Produkt na webu výrobce Popis:TIL4; CD282; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; TLR2
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NFkappaB activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophageactivating lipopeptide2kD (MALP2), soluble tuberculosis factor (STF), phenolsoluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspAL) cooperatively with TLR6.