Unconjugated Rabbit anti-Human, Mouse, Sheep, Rabbit VCAM1 Polyclonal Antibody [IgG]

CD106; INCAM-1; Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; VCAM1; L1CAM

Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.