Cy7 Rabbit anti- SOX22/SOX12 Polyclonal Antibody, Cy7 Conjugated [IgG]

Homo sapiens SRY sex determining region Y box 12; Protein SOX-22; SOX 12; SOX 12 protein; SOX 22; SOX 22 protein; sox12; SOX12 protein; SOX12_HUMAN; SOX22 protein; SRY sex determining region Y box 12; SRY sex determining region Y box 22; SRY box 12; SRY box 22; SRY related HMG box gene 22; Transcription factor Sox-12.

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.