ALEXA FLUOR 555 Rabbit anti-Human IQCK Polyclonal Antibody, ALEXA FLUOR 555 Conjugated [IgG]

Výrobce: Bioss Katalogové č.: bs-9023R-A555 Aplikace: Imunofluorescence Reaktivita: Human Původ: Rabbit Klonalita: Polyclonal Konjugát: Alexa Fluor 555 Laser: 550 nm (zeleno-žlutý) Podtřída: IgG Status: RUO Dodatečné informace: Produkt na webu výrobce Popis:

FLJ20115; FLJ36575; IQ domain containing protein K; MGC35048; IQCK_HUMAN.

Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. alternatively splicing events.

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