Unconjugated Rabbit anti-Human, Rat E2F5 Polyclonal Antibody [IgG]

E2F-5; Transcription factor E2F5; E2F5

Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.