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Biotin Rabbit anti-Human, Mouse, Rat AMPD3 Polyclonal Antibody, Biotin Conjugated [IgG]
Výrobce: Bioss Katalogové č.: bs-9517R-Biotin Aplikace: Western Blot, Imunohistochemie Reaktivita: Human, Mouse, Rat Původ: Rabbit Klonalita: Polyclonal Konjugát: Biotin/Purifikovaná Laser: Ostatní Podtřída: IgG Status: RUO Dodatečné informace: Produkt na webu výrobce Popis:Adenosine monophosphate deaminase isoform E; Adenosine monophosphate deaminase 3; AMP aminohydrolase; AMP deaminase 3; AMP deaminase isoform E; Ampd3; AMPD3_HUMAN; Erythrocyte AMP deaminase; Erythrocyte specic AMP deaminase; Erythrocyte type AMP deaminase; Myoadenylate deaminase.
AMP deaminase plays a critical role in energy metabolism.Involvement in diseaseDefects in AMPD3 are the cause of adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE); also known as erythrocyte AMP deaminase deficiency. AMPDDE is a metabolic disorder due to lack of activity of the erythrocyte isoform of AMP deaminase. It is a clinically asymptomatic condition characterized by a 50% increase in steady-state levels of ATP in affected cells. Individuals with complete deficiency of erythrocyte AMP deaminase are healthy and have no hematologic disorders.