PE Rabbit anti-Human, Mouse, Rat, Sheep Bcl-2 Polyclonal Antibody, PE Conjugated [IgG]

Bcl-2; PPP1R5; Apoptosis regulator Bcl-2; BCL2

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).