protilatky.sk
NFKBIA/IKB alpha Polyclonal Antibody, Biotin Conjugated
Výrobce: Bioss Katalogové č.: bs-1287R-Biotin Aplikace: Western Blot, Imunohistochemie, ELISA, ELISPOT Reaktivita: Human, Mouse, Rat, Chicken, Bovine Původ: Rabbit Klonalita: Polyclonal Konjugát: Biotin/Purifikovaná Laser: Ostatní Podtřída: IgG Status: RUO Dodatečné informace: Produkt na webu výrobce Popis:Nfkbi; AI46215; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Nfkbia; Ikba
Inhibits the activity of dimeric NFkappaB/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.