Unconjugated Mouse anti-Human, Mouse, Rat M2-PK Polyclonal Antibody [IgG]

Výrobce: Bioss Katalogové č.: bs-0102M Aplikace: Western Blot, Imunofluorescence, Imunohistochemie, ELISA, ELISPOT Reaktivita: Human, Mouse, Rat Původ: Mouse Klonalita: Polyclonal Podtřída: IgG Status: RUO Dodatečné informace: Produkt na webu výrobce Popis:

PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-30; Pyruvate kinase PKM; Cytosolic thyroid hormone-binding protein; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; Tumor M2-PK; p58; PKM; PK2

Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

100ul
11 340 Kč
bez DPH
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