Unconjugated Rabbit anti-Human, Mouse, Rat, Others, Zebrafish, Drosophila H3K27me3 Polyclonal Antibody [Not determined]

A core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.