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ALEXA FLUOR 647 Mouse anti-Human, Mouse, Rat Fibronectin (1B9) Monoclonal Antibody , ALEXA FLUOR 647 Conjugated [IgG]
Výrobce: Bioss Katalogové č.: bsm-33143M-A647 Aplikace: Imunofluorescence Reaktivita: Human, Mouse, Rat Původ: Mouse Klonalita: Monoclonal Konjugát: AlexaFluor647 Laser: 633 nm (červený) Podtřída: IgG Status: RUO Dodatečné informace: Produkt na webu výrobce Popis:Fibronectin; FN1; Cold-insoluble globulin; CIG
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.