Cy3 Rabbit anti-Human, Mouse, Rat GATA4 Polyclonal Antibody, Cy3 Conjugated [IgG]

TOF; ASD2; VSD1; TACHD; Transcription factor GATA-4; GATA-binding factor 4; GATA4

Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.