protilatky.sk
CD95 Polyclonal Antibody, Cy5 Conjugated
Výrobce: Bioss Katalogové č.: bs-0215R-Cy5 Aplikace: Western Blot, Imunofluorescence, Průtoková cytometrie Reaktivita: Human, Mouse, Rat, Monkey Původ: Rabbit Klonalita: Polyclonal Konjugát: Cy5 Laser: 633 nm (červený) Podtřída: IgG Status: RUO Dodatečné informace: Produkt na webu výrobce Popis:lpr; APO1; APT1; CD95; TNFR6; Tnfrsf6; AI196731; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; Fas
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase8 to the activated receptor. The resulting deathinducing signaling complex (DISC) performs caspase8 proteolytic activation which initiates the subsequent cascade of caspases (aspartatespecific cysteine proteases) mediating apoptosis. FASmediated apoptosis may have a role in the induction of peripheral tolerance, in the antigenstimulated suicide of mature Tcells, or both (By similarity).