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ALEXA FLUOR 488 Rabbit anti-Human, Mouse, Rat, Pig, Chicken HSP70 1A/1B Polyclonal Antibody, ALEXA FLUOR 488 Conjugated [IgG]
Výrobce: Bioss Katalogové č.: bs-0244R-A488 Aplikace: Western Blot, Průtoková cytometrie Reaktivita: Ostatní Původ: Rabbit Klonalita: Polyclonal Konjugát: AlexaFluor488 Laser: 488 nm (modrý) Podtřída: IgG Status: RUO Dodatečné informace: Produkt na webu výrobce Popis:HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A; HEL-S-103; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2; HSPA1A; HSX70
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.